A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. As part of our commitment to womens health, we offer the thinprep 2000 processor an automated slide preparation system for use with the thinprep pap. Comparison of thinprep and surepath liquidbased cytology. Obtain an adequate sample from the ectocervix using a plastic spatula. Hologic thinprep 2000 instructions for use manual pdf.
Since this is our pathology group website, the following is obviously the opinion of our decision makers and not the same as an official publication in an official medical or scientific journal. These instructions include the following statement. Quest diagnostics to offer cytyc s thinprep pap test. As part of our commitment to womens health, we offer the thinprep 2000 processor an automated slide.
Obtain a sample from the cervix using a broomlike device by inserting the brush portion into the cervical os and then rotate the brush five times. Thinprep 3000 processor, cytyc, marlboro, ma pdf report indicates whether the report includes an additional document with charts, images or other enriched information. Comparison of thinprep and surepath liquidbased cytology and subsequent human papillomavirus dna testing in china fanghui zhao, md, phd 1. The ancillary kit formulated for this specific application is the genprobe. Free search pdf free unlimited document files search. Preservcyt solution liquid pap specimens processed using the thinprep 3000 processor or other instruments have not been evaluated to test for chlamydia trachomatis and neisseria gonorrhoeae. Thinprep plus papanicolaou stain method is more sensitive. Through hologics computerized process and patented membrane technology, the thinprep 2000 processor controls dispersion, collection and transfer of diagnostic cells from sample to slide. Lubricant use during pap test collection for the thinprep pap dear colleague. The thinprep 5000 autoloader system maximizes laboratory efficiency while offering even more walkaway freedom with up to 8 hours of handsfree processing of thinprep pap test, thinprep nongyn and thinprep urocyte samples. Automatic sample preparation system thinprep 2000 hologic. At the laboratory, the preservcyt sample vial is placed into a thinprep 2000 processor and a gentle dispersion step breaks up blood, mucus, nondiagnostic debris, and thoroughly mixes the cell sample.
At the laboratory, the preservcyt sample vial is placed into a thinprep 2000 processor and a. Page 115 the thinprep 2000 system operators manual contains detailed information about the thinprep 2000 system, such as the principles of operation, operating instructions, specifications, and maintenance information. The manual pap smear is the primary procedure for screening the population for cervical. William f hancock, md 1447 york court, burlington, nc 27215. Wang 2000 fibroadenoma mimicking papillary carcinoma on thinprep of fineneedle aspiration of the breast. The versatile workhorse that started the thinprep revolution. Thinprep ctcprocessed and control samples 900 ll were transferred into thinprep preservcyt containers hologic, bedford, mass and processed with the thinprep 2000 system hologic with the fineneedle aspiration program. Salivary gland fine needle aspiration using the thinprep. Cases are examined microscopically and those with appropriate cytologic diagnoses are referred for human papillomavirus hpv testing if the patient is 21 or older. We are looking for a users manual for a cytyc thinprep 2000 processor if anyone happens to have one we would greatly appreciate it.
The thinprep 2000 automaton allows thinlayer cell preparations to be provided thanks to a filtration process. Slides used with this system must first be prepared on a thinprep 2000 or 3000 processor, and stained with thinprep stain. Surepath samples yielded higher sensitivities and similar specificities. Hologic thinprep 2000 instructions for use manual pdf download. Methods information on all cervix uteri cytological and histological tests in the netherlands registered from january 2000 until march 20 was retrieved from palga. Since introduction, cytyc has manufactured more than 1,000 thinprep 2000 processors and 10 million thinprep pap tests for cervical cancer screening. Pdf analysis of urine cytology tests in 120 paired cases.
The thinprep pap test is the first significant improvement to the conventional pap smear in over 50 years. Fibroadenoma mimicking papillary carcinoma on thinprep of. The thinprep system consists of the thinprep 2000 processor and related reagents, filters, and other supplies. Food and drug administration in may of 1996, as a replacement for the conventional pap smear preparation. P224 comparing conventional cytology, thinprep and. Cytology categorization vs manual thinprep pap test. For the thinprep method, the csf samples were added to 10 ml preservcyt cell preservation solution, mixed, and allowed to stand for 15 min. Cytyc and quest diagnostics announce multiyear agreement. The thinprep system from hologic features gyn and nongyn testing with easytouse processors and.
The format summarizes the morphologic features common to specific diagnostic entities. The preservcyt solution, a component of the thinprep 2000 system, has been validated as an alternative medium for testing with aptima combo 2 assay. Refurbished cytyc thin prep 2000 tissue processor for sale. To reduce the chance of contaminating other specimens, work with one thinprep liquid pap specimen at a time. The thinprep system from hologic features gyn and nongyn testing with easyto use processors and. Thinprep pap test carpenter 1999 cancer cytopathology. Original paper comparing surepath, thinprep, and conventional cytology as primary test method. On fineneedle aspiration fna cytology, many cases of fibroadenoma display characteristic morphologic features that lead to a definitive diagnosis. Up to 60,000 samples per year with a single 8hour shift.
Run on thinprep 2000 processor using sequence 5 urocyte or thinprep 5000 on sequence urocyte. Nongyn specimens that need no preservative must be refrigerated until transport. Aptima combo 2 assay package insert ilex medical ltd. The role of thinprep cytology in the investigation of sln. Restoring satisfactory status in thinprep pap test. Preservcyt solution is an alcoholbased, preservation solution that serves as a transport, preservative, and antibacterial medium for gynecologic samples. How the pap test protects your patients contemporary obgyn. System, the thinprep 3000 processor, and the thinprep 5000 processor. In addition, the thinprep 2000 processor is compatible with nongynecological specimens to assist in the diagnosis of disease entities and cancers of numerous body sites obtained through exfoliative methods as well as by fine needle. Cell block ctcprocessed and control specimens 900 ll were cen.
Doclive free unlimited document files search and download. Slides were prepared using the thinprep 2000 automated slide processor hologic, bedford, ma, usa, fixed in 95% ethanol for 15 min, and stained by standard pap method, following the manufacturers. Swirl vigorously in the thinprep vial 10 times and discard the spatula. Hologic thinprep 2000 processor for sale mercedes scientific. Then, rotate the brush in the preservcyt solution 10 times while pushing against the wall of the thinprep vial. The resulting thinprep slides were papanicolaoustained. Conventional liquidbased techniques versus cytyc thinprep. A thin layer of cells is then transferred to a glass slide in a.
The manual also contains information on the solutions and materials required to prepare slides with the thinprep 2000 processor. Hologic thinprep 2000 operators manual pdf download. A thinprep pap specimen is collected, processed on a t2000 or t5000 processor, and stained with a pap stain. Guidos bj selvaggi sm detection of endometrial adenocarcinoma with the thinprep pa test d agn cytopathol 2000. Cytyc corporation develops, manufactures, and markets the thinprep system for medical diagnostic applications.
Fibroadenoma of the breast is the most common breast tumor in young women. Store the aliquot in aptima tube at 15c to 30c for transport to labcorp. Swirl the brush vigorously to release additional material. Refer to hologics thinprep pap test quick reference guides, part no. The transcyt filter rotates within the sample vial.
The thinprep 2000 processor utilises mechanical, pneumatic and fluidic principles for cell dispersion, collection and transfer. A semiautomated sample preparation instrument to prepare. Hologiccytyc thin prep 2000 for sale, refurbished, complete, in excellent functional and cosmetic condition. Recap the thinprep liquid pap specimen for pap smear processing. Comparing surepath, thinprep, and conventional cytology as. Its mixing action permits the preparation of multiple slides of. The thinprep 2000 processor is compatible with the thinprep pap test, thinprep nongyn, and thinprep urocyte samples. At the laboratory, the preservcyt sample vial is placed into a thinprep 2000. What are the current ordering options for hpv reflex testing. Compared with surepath samples, thinprep samples had higher rates of unsatisfactory cytology 0. Premarket approval of cytyc corporations thinprep 2000 system.
Methods conclusions primary screening with thinprep leads to higher interval cancer rates as compared to conventional cytology and surepath, suggesting a lower sensitivity to detect clinically relevant cin lesions. Lubricant use during pap test collection for the thinprep pap. It is important to note that lubricant increases the risk of contaminating or obscuring the. If pap is negative reflex to hpv high risk and if positive then hpv genotyping 16. Put on clean gloves and repeat steps 8 to 18 with subsequent specimens. Singlesample processing reduces risk of chainofcustody errors. On occasion we are asked to provide information concerning the use of lubricants when collecting a pap test. Comparison of thinprep and surepath liquidbased cytology and. Hologiccytyc thin prep 2000 for sale, refurbished, complete, in excellent functional and. Also known as the imager, this system appeared on the market in 2004 and was rapidly adopted by many high.
Cytyc thinprep 2000 processor service technicians forum. It prepares a monolayer of cells on a glass slide from cells collected in an alcohol. Surepath or thinprep are the preferred gynecological collection methods for pamlpshmc. This unit has been refurbished and includes a full parts and labor warranty. Analysis of urine cytology tests in 120 paired cases. As part of our commitment to womens health, we offer the thinprep 2000 processor an automated slide preparation system for use with the thinprep pap test. A vacuum is then applied to the filter, which collects cells on a 5. Thinprep imaging system operation summary and clinical information. The preservcyt solution component of the thinprep 2000 system is an. When ordering the pap test, select one of the following options for hpv reflex testing. The purpose of this study was to compare tp performance and biopsy follow. The thinprep 2000 processor, is a reliable automated slide preparation system.
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